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XB-PHENO-27370

Xtr Wt + foxi2 MO, Hendrickson CL et al. (2025)

Experiment + Assay: Xtr Wt + foxi2 MO + NF27-28 (whole-mount microscopy)
Background: Xtr.Nigerian1NXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection foxi2 MO1 foxi2
 NF stage 1 animal cap
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 27 to NF stage 28  
Anatomical Phenotypes: abnormal embryo morphology, abnormal ventral trunk, absent tail region, decreased size of the head
Expression Phenotypes (7):
decreased amount dlx3 expression in the animal cap
decreased amount dlx5 expression in the animal cap
decreased amount foxi1 expression in the animal cap
decreased amount krt70 expression in the animal cap
decreased amount lhx5 expression in animal cap
decreased amount tfap2a expression in the animal cap
decreased amount tp63 expression in animal cap
Source: Fig. 4BE
Article: XB-ART-61574, PubMed