Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-27353

Xtr Wt + cfap53 MO, Kulkarni SS et al. (2024)

Experiment + Assay: Xtr Wt + cfap53 MO + NF27-29/30 (in situ hybridization)
Background: Xtr.Nigerian AKhok
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection cfap53 MO5 cfap53
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 27 to NF stage 29 and 30  
Expression Phenotypes (3):
mislocalised dand5 expression in left-right organizer
mislocalised pitx2 expression in lateral plate mesoderm
increased amount pitx2 expression in lateral plate mesoderm
Human Disease Associations: visceral heterotaxy
Source: Fig. S1CDEF
Article: XB-ART-61041, PubMed