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XB-PHENO-27335

Xla Wt + DEX (NF17) + Tg(Xla.nkx2-1-GR), Hyatt BA et al. (2025)

Experiment + Assay: Xla Wt + DEX (NF17) + Tg(Xla.nkx2-1-GR) + NF39 (in situ hybridization)
Background: Xla.Inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
transgenesis Tg(Xla.nkx2-1-GR) nkx2-1 (Xla)
 NF stage 4 (8-cell) dorsal vegetal hemisphere blastomere
chemical dexamethasone
NF stage 17 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 39  
Expression Phenotypes (3):
mislocalised sftpc.L expression in hindgut endoderm
increased amount sftpc.L expression in lung bud
mislocalised sftpc.L expression in midgut
Source: Fig1E c1r2
Article: XB-ART-61398, PubMed