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XB-PHENO-27334

Xla Wt + Tg(Xla.nkx2-1-GR) [HG], Hyatt BA et al. (2025)

Experiment + Assay: Xla Wt + Tg(Xla.nkx2-1-GR) [HG] + NF39 (in situ hybridization)
Background: Xla.Inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
transgenesis Tg(Xla.nkx2-1-GR) nkx2-1 (Xla)
 NF stage 4 (8-cell) ventral vegetal hemisphere blastomere
chemical dexamethasone
NF stage 13
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 39  
Expression Phenotypes (4):
decreased amount cdx2.L expression in midgut primordium
decreased amount fabp2.L expression in midgut primordium
mislocalised sftpc.L expression in hindgut
mislocalised sox2.L expression in dorsal lateral plate mesoderm
Source: Figh. 1C c3
Article: XB-ART-61398, PubMed