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XB-PHENO-27212

Xtr Wt + cyp21a2 CRISPR, Paul B et al. (2022)

Experiment + Assay: Xtr Wt + cyp21a2 CRISPR + NF54-62 (RT-PCR)
Background: Xtr.Nigerian1NXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR cyp21a2 gRNA1 cyp21a2
 NF stage 1 whole organism
lineage tracer mCherry
NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
RT-PCR NF stage 54 to NF stage 62  
Anatomical Phenotypes: abnormal hormone metabolic process
Expression Phenotypes (3):
decreased amount klf9 expression in brain
decreased amount klf9 expression in tail
decreased amount ush1g expression in tail
Source: Fig. 4 ABC
Article: XB-ART-59422, PubMed