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XB-PHENO-27199

Xla Wt + Xtr.sox21, Damuth DL et al. (2024)

Experiment + Assay: Xla Wt + Xtr.sox21 + NF37/38 (in situ hybridization)
Background: Xla.J-strainNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection sox21 sox21
 NF stage 2- whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 37 and 38  
Anatomical Phenotypes: absent eye
Expression Phenotypes (5):
absent rax.L expression in eye
increased amount sox3.L expression in brain
absent sox3.L expression in lens
increased amount sox3.L expression in neural tube
increased amount sox3.L expression in olfactory region
Source: Fig. 2b
Article: XB-ART-60837, PubMed