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XB-PHENO-26955

Xtr Wt + acbd6 CRISPR (68), Kaiyrzhanov R et al. (2024)

Experiment + Assay: Xtr Wt + acbd6 CRISPR (68) + NF45 (3D imaging)
Background: Xtr.Nigerian1EXRC
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR acbd6 gRNA1 acbd6
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
3D imaging NF stage 45  
Anatomical Phenotypes: abnormal brain morphology, abnormal craniofacial region, abnormal eye morphology, abnormal jaw muscle, abnormal midbrain morphology, absent eye
Human Disease Associations: microphthalmia
Source: Fig. 5 G
Article: XB-ART-60415, PubMed