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XB-PHENO-25896

Xtr Wt + ENU, Nakayama T et al. (2017)

Experiment + Assay: Xtr Wt + ENU + NF46-47 (whole-mount microscopy)
Background: Xtr.NigerianGrnger
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
chemical Ethylnitrosourea
NF stage 2 (2-cell)
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 46 to NF stage 47  
Anatomical Phenotypes: abnormal inner ear morphology, abnormal sacculus, absent auditory ossicle, absent sacculus, absent utricle, decreased size of the utricle, increased size of the otic vesicle
Human Disease Associations: Hermansky-Pudlak syndrome
Source: Fig. 6 C, E-H
Article: XB-ART-52468, PubMed