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XB-PHENO-24754

Xtr Wt + ift70a CRISPR, Getwan M et al. (2021)

Experiment + Assay: Xtr Wt + ift70a CRISPR + NF62-63 (Other Detection Assay)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR ift70a gRNA1 ift70a
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
Other Detection Assay NF stage 62 to NF stage 63  
Anatomical Phenotypes: abnormally increased number of digit, decreased length of forelimb, decreased length of hindlimb
Human Disease Associations: kidney disease, ciliopathy, polydactyly
Source: Fig. 4 D, Sup. Fig. 5 f h
Article: XB-ART-58465, PubMed