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XB-PHENO-24401

Xla Wt + fto MO, Kim H et al. (2021)

Experiment + Assay: Xla Wt + fto MO + NF20 (in situ hybridization)
Background: Xla.Inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection fto MO1 fto (Xla)
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 20 to NF stage 20  
Anatomical Phenotypes: abnormal development of left-right axis
Expression Phenotypes (1):
mislocalised dand5.L expression in gastrocoel roof plate
Human Disease Associations: visceral heterotaxy 5, visceral heterotaxy
Source: Fig. 1 B
Article: XB-ART-57939, PubMed