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XB-PHENO-24178

Xla Wt + chd1 MO + BMS453, Wyatt BH et al. (2021)

Experiment + Assay: Xla Wt + chd1 MO + BMS453 + NF29/30-31 (whole-mount microscopy)
Background: Xla.Inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection chd1 MO1 chd1 (Xla)
 NF stage 1
chemical BMS 453
NF stage 23 whole organism
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 29 and 30 to NF stage 31  
Anatomical Phenotypes: abnormal craniofacial region morphology, decreased size of the intercanthal region, decreased width of the mouth
Human Disease Associations: orofacial cleft
Source: Fig. 7 g
Article: XB-ART-57345, PubMed