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XB-PHENO-24104

Xtr Wt + dlg5 CRISPR, Marquez J et al. (2021)

Experiment + Assay: Xtr Wt + dlg5 CRISPR + NF45 (immunohistochemistry)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR   dlg5
 NF stage 1
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 45 to NF stage 45 Tuba4b Ab9
Anatomical Phenotypes: abnormally decreased number of cilium in the pronephric kidney, increased size of the proximal tubule
Human Disease Associations: ciliopathy
Source: Fig. S3 B
Article: XB-ART-57158, PubMed