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XB-PHENO-23811

Xtr wt+ nup205 MO, Marquez J et al. (2021)

Experiment + Assay: Xtr wt+ nup205 MO + NF 28
Background: Xtr.Nigerian AKhok
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection nup205 MO1 nup205
 NF stage 2 (2-cell) whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28 to NF stage 28  
transmission electron microscopy NF stage 28 to NF stage 28  
Anatomical Phenotypes: abnormally decreased number of cilium in the mucociliary epithelium, abnormal multiciliated epidermal cell
Expression Phenotypes (1):
decreased amount tubb2b expression in multiciliated epidermal cell
Human Disease Associations: ciliopathy
Source: Fig. 2 B
Article: XB-ART-57453, PubMed