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XB-PHENO-2351

Xla Wt + kmt2d MO, Schwenty-Lara J et al. (2020)

Experiment + Assay: Xla Wt + kmt2d MO + NF 25
Background: Xla.Portsmouth1EXRC
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection kmt2d MO1 kmt2d.L
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 25 to NF stage 25  
Anatomical Phenotypes: abnormal neural crest morphology
Expression Phenotypes (2):
mislocalised twist1.L expression in branchial crest
decreased amount twist1.L expression in cranial neural crest
Source: Fig 2D row2 col2
Article: XB-ART-56551, PubMed