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XB-PHENO-20845

Xla Wt + atp6v0cdel, Vandenberg LN et al. (2011)

Experiment + Assay: Xla Wt + atp6v0cdel + NF45-48 (whole-mount microscopy)
Background: Xla.Inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(atp6v0cdel) atp6v0c.L
atp6v0c.S
 NF stage 1 blastomere
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 45 to NF stage 48  
Anatomical Phenotypes: abnormal brain morphology, absent olfactory pit, increased pigmentation in the optic nerve, increased thickness of the optic nerve
Source: Fig 3 I
Article: XB-ART-43550, PubMed