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XB-PHENO-20191

Xla Wt + pdx1-GR + ptf1a-GR + DEX, Afelik S et al. (2006)

Experiment + Assay: Xla Wt + pdx1-GR + ptf1a-GR + DEX + NF48 (in situ hybridization)
Background: Xla.Inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(ptf1a.L-GR) ptf1a.S
ptf1a.L
 NF stage 4 (8-cell) blastomere
mRNA injection Tg(pdx1.L-GR) pdx1.S
pdx1.L
 NF stage 4 (8-cell) blastomere
chemical dexamethasone
NF stage 27 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 48  
Anatomical Phenotypes: abnormal duodenum morphology, abnormal stomach morphology, decreased size of the duodenum, decreased size of the stomach, increased size of the pancreas
Source: fig.4.3
Article: XB-ART-261, PubMed