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Summary Attributions Wiki
XB-GRNA-23659145
gRNA Name: smad6 gRNA1
Synonyms: smad6_g1
Genomic Target: smad6

PAM Sequence: AGG
Sequence: 5' GAATCTGGAAAACCGGAGTG 3'



Genomic Target tropicalis laevis.L laevis.S
Identities 20/20 18/20 19/20
genome
gRNA
 
5' CACTCCGGTTTTCCAGATTC 3'
   ||||||||||||||||||||
3' GTGAGGCCAAAAGGTCTAAG 5'
 
5' CGCTCCGGTTTTCCAGATTG 3'
   | ||||||||||||||||| 
3' GTGAGGCCAAAAGGTCTAAG 5'
 
5' CACTCCGGTTTTCCAGATTG 3'
   ||||||||||||||||||| 
3' GTGAGGCCAAAAGGTCTAAG 5'
    
Genomic Alignments Position Identity Strand Target Genomic Target
laevis 9.2 chr3S:35721634..35721653 19/20 Antisense target smad6.S
chr3L:108458297..108458316 18/20 Sense target smad6.L
chr5L:35503969..35503988 17/20 Sense off-target LOC108716608
chr1S:148037591..148037610 17/20 Antisense unknown
chr3L:111262381..111262400 17/20 Antisense unknown
chr3S:114863444..114863463 17/20 Sense unknown
chr6L:121937257..121937276 16/20 Antisense unknown
tropicalis 10.0 Chr3:117294525..117294544 20/20 Sense target smad6
Chr3:140104489..140104508 17/20 Antisense off-target plppr2
Chr3:140104489..140104508 17/20 Antisense off-target tmem205
Chr10:42719203..42719222 17/20 Sense off-target LOC101734097
Chr2:168018964..168018983 16/20 Sense unknown
Chr3:55616503..55616522 16/20 Antisense unknown
Publications
???morpholino.displaySummary.papersFirst??? Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos., Sci Rep 2020     
???morpholino.displaySummary.papersRecent??? Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas., HGG Adv 2022     
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