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Antibody Name: Polr2a Ab1 Common Name: RRID: Synonyms: Antigens Gene: polr2a Clone Type: Monoclonal Source: Eurogentec/Covance

Antibody
Clone Number	H5
Purification	Ascites
Isotype	IgM
Host Organism	mouse
Xenopus Reactivity	X. tropicalis
Non-Xenopus Reactivity
Description:	Supplied by Covance, cat# MMS-129R The antibody H5 was developed against a purified phosphorylated form of RNA polymerase II extracted from a transformed cell line. Pol II has two physiologically important phosphorylation sites; ser-2 and ser-5. Both sites are found in the heptapeptide repeat YSPTSPS at the C-terminal domain. This antibody recognizes the phosphoserine 2 version of pol II.
Immunogen
Name	RNA Pol II (S2)
Type	polypeptide
Post Translational Modifications	Phosphorylated
Source Organism	Other
Description
Sequence
Reported Usage
immunohistochemistry	Dilution 1:50, 1:100
Publications
???displayAntibody.papersFirst???	Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes., Genes Dev 2011
???displayAntibody.papersRecent???	Xenopus Nanos1 is required to prevent endoderm gene expression and apoptosis in primordial germ cells., Development 2012
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