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XB-ANTIBODY-14578978

Antibody Name: Ctnnb1 Ab1

Common Name: Active Beta-catenin

RRID: RRID:AB_309887
Synonyms: 05-665, anti-ABC, beta-catenin, dephospho-beta-catenin (S37/T41)
Antigens
Gene: ctnnb1
Clone Type: Monoclonal
Source: Millipore

Antibody
Clone Number 8E7
Purification Immunoglobulin Fractionation
Isotype IgG1
Host Organism mouse
Xenopus Reactivity X. tropicalis, X. laevis
Non-Xenopus Reactivity human, mouse, rat
Description: Supplied by Millipore catalog #05-665
Immunogen
Name beta-catenin
Type polypeptide
Post Translational Modifications Proteolysis
Source Organism human
Description The epitope corresponds to amino acid residues 36-44 of human beta-catenin. Recognizes active form of beta-catenin, dephosphorylated on Ser37 or Thr41. The immunogen was a fusion protein corresponding to residues 1-100 of human beta-catenin with a c-terminal histidine tag
Sequence [+]
Reported Usage
western blot 1:1000
Publications
???displayAntibody.papersFirst??? Barhl2 limits growth of the diencephalic primordium through Caspase3 inhibition of beta-catenin activation., Proc Natl Acad Sci U S A 2011     
???displayAntibody.papersRecent??? Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., J Biol Chem 2022     
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