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Summary Expression Gene Literature (140) GO Terms (2) Nucleotides (3) Proteins (5) Interactants (43) Wiki
ECB-GENEPAGE-23049519
???displayGene.symbol??? :
 h2a
Symbol Status : Partially Curated


???displayGene.name???: 
histone h2A
Name Status : Partially Curated


???displayGene.synonyms???
EhH2a , EhH2a_1 , EhH2a_10 , EhH2a_11 , EhH2a_12 , EhH2a_13 [+] ( Nomenclature history )

???displayGene.geneFunction???
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the

Protein Function :
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central ro...[+]


InterPro :
Histone H2A CS, Histone-fold, Histone H2A/H2B/H3, Histone H2A, [+]

???displayGene.geneInteractants???
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Diseases: 


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