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Antibody Name: LOC580458 Ab1 Common Name: sushi domain-containing protein 2 RRID: Synonyms: SpMesh, SpSusd2 Antigens Gene: LOC580458 Clone Type: Polyclonal Source:

Antibody
Clone Number
Purification
Isotype	IgG
Host Organism	rabbit
Echinoderm Reactivity	S. purpuratus, H. pulcherrimus
Non-Echinoderm Reactivity
Description:	Reacts with a ~120 kDa protein that localizes to septate junctions of the midgut and hindgut. Generated by Kiwa Laboratory Animals (Wakayama, Japan) for initial usage by the Heyland lab at the University of Guelph in Canada.
Immunogen
Name	HpMesh
Type	polypeptide
Post Translational Modifications	None
Source Organism	Hemicentrotus pulcherrimus
Description	Glutathione-S-transferase fusion protein generated using an amino acid-fragment representing the C-terminal cytoplasmic region, which was amplified using the forward primer, 5'-acgcgtcgacAAAACCAATAGCAGCTACCCAAGGAAATCG-3', and the reverse primer, 5'-acgcgtcgacCTAAATCCACCCACCAGTACCTTTGATGGT-3'.
Sequence
Reported Usage
immunofluorescence
western blot
immunohistochemistry
Publications
???displayAntibody.papersFirst???	Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier., Dev Biol 2023
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