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ECB-ART-55133
Sci Data 2026 Jun 23; doi: 10.1038/s41597-026-07660-y.
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Metamorphosis of the purple sea urchin Heliocidaris crassispina: Single-cell transcriptomic datasets.

Zhao T, Ge H, Huang Y, Wang Y, Zhang L, Wang G.


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Metamorphosis is an obligate developmental transition for most marine invertebrates with a biphasic life cycle, representing a critical ontogenetic phase. This process involves extensive morphological and physiological changes that incur high mortality, thereby regulating population dynamics. This study establishes a single-cell transcriptomic atlas of larval and juvenile Heliocidaris crassispina, providing a comprehensive analysis at single-cell resolution. eight distinct cell types were identified: digestive, epithelial, germ, immune, muscle, nerve, proliferating, and skeletogenic cells. These findings establish a foundation for future research into invertebrate metamorphosis at the single-cell level.

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