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ECB-ART-51920
Dev Growth Differ 1974 Jan 01;162:75-82. doi: 10.1111/j.1440-169X.1974.00075.x.
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INTERACTIONS OF 1-METHYLADENINE AND THE SURFACE OF STARFISH OOCYTE.

Shortridge K , Losek B , Lee HH .


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Three metabolic inhibitors, mycostatin, concanavalin A (Con A) and cytochalasin B (CB) were used to study the interactions between l-methyladenine (1-MA) and the starfish oocyte surface leading to germinal vesicle breakdown (GVB). Mycostatin and Con A had no obvious effects on GVB. CB did not inhibit, but did delay GVB. This delaying effect was interpreted as having multiple 1-MA reactive "sites" on the surface. The results also suggested that not all of them were needed to react with 1-MA to bring about GVB.

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