ECB-ART-30369
Cell Differ
1977 Aug 01;62:111-8. doi: 10.1016/0045-6039(77)90033-1.
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''Cleavage fields'': hypothesis on early embryonic development.
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The hypothesis is put forward that events of the early embryonic development can be interpreted on the basis of a radial distribution of cytoplasmic components, i.e. of a ''cleavage field'', progressively established during the growth of the oocyte. The orientations of the cleavage spindles and the corresponding furrows'' positions are assumed to be correlated to the field''s temporal evolution which, in turn, is determined by flows of cytoplasmic components originated by the changes in the membrane shape. From this viewpoint, a simple explanation of egg regulation is proposed, and the particular case of the sea urchin embryo is briefly discussed.
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Genes referenced: LOC100887844